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Moderate drinking can reduce risks of Alzheimer’s

January 4, 2009



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Moderate drinkers often have lower risks of Alzheimer’s disease and other cognitive loss, according to researchers who reviewed 44 studies.

In more than half of the studies, published since the 1990s, moderate drinkers of wine, beer and liquor had lower dementia risks than nondrinkers and appear to receive certain health benefits. In only a few studies were there increased risks.

“Alcohol is a two-edged sword,” said Michael Collins, Ph.D., a professor and neuroscientist at Loyola University Chicago Stritch School of Medicine and lead author of the refereed report in the journal Alcoholism: Clinical and Experimental Research. “Too much is bad. But a little might actually be helpful.”

Moderate alcohol consumption generally is defined as 1 drink or less per day for women and 1-2 drinks or less per day for men.

Long-term alcohol abuse can cause memory loss and impair cognitive function. It’s unknown why moderate alcohol use appears to have the opposite effect. One theory is that the well-known cardiovascular benefits of moderate alcohol consumption also can reduce the risk of mini strokes that cause dementia.

Collins and another Loyola professor, neuroscientist Edward Neafsey, Ph.D., suggest a second possible explanation. Small amounts of alcohol might, in effect, make brain cells more fit. Alcohol in moderate levels stresses cells and thus toughens them up to cope with major stresses down the road that could cause dementia.

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